Phenotypes Associated with This Genotype

Genotype
MGI:3817326

• Allelic Composition: Kcnn2^m1Btlr/Kcnn2^m1Btlr
• Genetic Background: C57BL/6J-Kcnn2^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:137501 )

• at three weeks of age, homozygous mutant mice are significantly smaller than their littermates

behavior/neurological

tremors ( J:137501 )

• mice homozygous for this mutation exhibit a tremor of variable severity

hunched posture ( J:137501 )

• mutant mice, some as young as 3 months of age, develop a hunched posture

abnormal gait ( J:137501 )

• the tremor is often accompanied by stiff and deliberate hindfoot placement during locomotion, particularly in older mutants

abnormal sexual interaction ( J:137501 )

♂ • although both male and female homozygotes are fertile, mutant males do not breed

♂ • homozygous mutant females are able to breed

integument

abnormal coat appearance ( J:137501 )

• the coats of mutant mice, some as young as 3 months of age, become dull and lack-luster