Analysis Tools
mortality/aging
 N |
• premature death in male Mecp2-null mice at 10-11 weeks is rescued
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behavior/neurological
|
N |
• neurological abnormalities seen in single transgenic mutant are rescued by loss of Mecp2
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nervous system
|
N |
• amplitudes of EPSCs, RRP size, and mEPSC frequency, amplitude, and decay kinetics are normalized in double mutant brains compared to either single mutant brain
• glutamatergic synaptic density is normalized in double mutant brains compared to either single mutant brain
|
