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Phenotypes Associated with This Genotype
Genotype
MGI:3815303
Allelic
Composition
Cd36tm1Frm/Cd36tm1Frm
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd36tm1Frm mutation (0 available); any Cd36 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• primary microglial cultures fail to exhibit activation following treatment with SNCA unlike wild-type cells and produce less cellular reactive oxygen species than similarly treated wild-type cells

nervous system
• primary microglial cultures fail to exhibit activation following treatment with SNCA unlike wild-type cells and produce less cellular reactive oxygen species than similarly treated wild-type cells

hematopoietic system
• primary microglial cultures fail to exhibit activation following treatment with SNCA unlike wild-type cells and produce less cellular reactive oxygen species than similarly treated wild-type cells

cellular
• primary microglial cultures fail to exhibit activation following treatment with SNCA unlike wild-type cells and produce less cellular reactive oxygen species than similarly treated wild-type cells


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory