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Phenotypes Associated with This Genotype
Genotype
MGI:3815076
Allelic
Composition		 Cthrc1tm1Hssk/Cthrc1tm1Hssk
Vangl2Lp/Vangl2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cthrc1tm1Hssk mutation (1 available); any Cthrc1 mutation (34 available)
Vangl2Lp mutation (2 available); any Vangl2 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal cochlear hair cell morphology ( J:140886 )
• orientation is significantly disrupted
• organization of hair cells is normal
abnormal cochlear inner hair cell morphology ( J:140886 )
• disruptions are most severe for inner hair cells

nervous system
abnormal cochlear hair cell morphology ( J:140886 )
• orientation is significantly disrupted
• organization of hair cells is normal
abnormal cochlear inner hair cell morphology ( J:140886 )
• disruptions are most severe for inner hair cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory