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Phenotypes Associated with This Genotype
Genotype
MGI:3814903
Allelic
Composition
Six3tm3Gco/Six3tm3Gco
Foxg1tm1(cre)Skm/Foxg1+
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1tm1(cre)Skm mutation (2 available); any Foxg1 mutation (11 available)
Six3tm3Gco mutation (0 available); any Six3 mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• many display a phenotype typical of holoprosencephaly
• anterior diencephalon is normal

Mouse Models of Human Disease
OMIM ID Ref(s)
Holoprosencephaly 2; HPE2 157170 J:140315


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/17/2016
MGI 6.03
The Jackson Laboratory