Phenotypes Associated with This Genotype

Genotype
MGI:3814176

• Allelic Composition: Pkhd1^tm1Cjwa/Pkhd1^tm1Cjwa
• Genetic Background: C.129S6-Pkhd1^tm1Cjwa

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

kidney cyst ( J:140302 )

abnormal proximal convoluted tubule morphology ( J:140302 )

• attenuation of the brush border is seen in females that develop cystic changes at 3 months of age

dilated proximal convoluted tubule ( J:140302 )

• Background Sensitivity: dilation is detected in proximal tubules of congenic female mice by 3 months of age compared to 9 months of age in mice on a mixed background

growth/size/body

kidney cyst ( J:140302 )