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Phenotypes Associated with This Genotype
Genotype
MGI:3813519
Allelic
Composition		 Tcrdtm1Mom/Tcrdtm1Mom
Tcrgtm2.1Dhr/Tcrgtm2.1Dhr
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcrdtm1Mom mutation (13 available); any Tcrd mutation (16 available)
Tcrgtm2.1Dhr mutation (0 available); any Tcrg mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell receptor gamma chain V-J recombination ( J:75624 )
• Vgamma2 rearrangement is reduced by 2-fold in the adult thymus compared to Tcrdtm1Mom homozygotes

hematopoietic system
abnormal T cell receptor gamma chain V-J recombination ( J:75624 )
• Vgamma2 rearrangement is reduced by 2-fold in the adult thymus compared to Tcrdtm1Mom homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory