Phenotypes Associated with This Genotype

Genotype
MGI:3812429

• Allelic Composition: Zeb1^tm1Yhi/Zeb1⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal iridocorneal angle ( J:135179 )

• iridocorneal adhesions lead to loss of the iridocorneal angle

anterior iris synechia ( J:135179 )

• iridocorneal adhesions are observed in 4 month old mice

• corneolenticular and iridolenticular adhesions are also evident

increased cornea thickness ( J:135179 )

• the cornea of 4 month old mice is more than twice as thick as controls

abnormal cornea stroma morphology ( J:135179 )

• there number of keratocytes found in the cornea are doubled in 4 month old mice compared to age-matched controls