Phenotypes Associated with This Genotype

Genotype
MGI:3810400

• Allelic Composition: Cacna1a^tm2Hzo/Cacna1a^tm2Hzo
• Genetic Background: involves: 129S/SvEv

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal channel response ( J:139488 )

• barium current density of the calcium ion channel is decrease compared to in wild-type cells likely due to decreased calcium ion channel abundance

• however, voltage dependent activation and inactivation of the calcium ion channel is normal

behavior/neurological

behavior/neurological phenotype ( J:139488 )

N • mice exhibit normal behavior beyond 20 months of age