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Phenotypes Associated with This Genotype
Genotype
MGI:3810255
Allelic
Composition
Arr3tm1Chcr/Arr3tm1Chcr
Sagtm1Jnc/Sagtm1Jnc
Genetic
Background
involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arr3tm1Chcr mutation (0 available); any Arr3 mutation (11 available)
Sagtm1Jnc mutation (9 available); any Sag mutation (43 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• cones exhibit a greatly slowed recovery from strong flashes compared to wild-type cones
• the amplitude of slow tails of recovery are increased compared to in wild-type mice
• S- and M-cone opsin driven dim-flash responses exhibit slow tail in recovery unlike wild-type mice
• however, the peak time of dim-flash response is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory