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Phenotypes Associated with This Genotype
Genotype
MGI:3810083
Allelic
Composition		 Traddtm1.1Zgl/Traddtm1.1Zgl
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Traddtm1.1Zgl mutation (0 available); any Tradd mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased physiological sensitivity to xenobiotic ( J:139031 )
• Resistant to TNF induced hepatitis (mice treated first with D-galactosamine and then with TNF)
• mouse embryo fibroblasts are resistant to TNF induced apoptosis and necrosis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory