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Phenotypes Associated with This Genotype
Genotype
MGI:3809816
Allelic
Composition
Cdh13tm1Brns/Cdh13tm1Brns
Genetic
Background
involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdh13tm1Brns mutation (1 available); any Cdh13 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• hypoxia-induced retinal vasculature exhibits a 63% reduction in vascular glomeruli and a 53% reduction in vessel branching compared to in wild-type mice

homeostasis/metabolism
• serum adiponectin levels are increased compared to in wild-type mice

reproductive system
N
• mammary gland development and function are normal

neoplasm
N
• mice exhibit no spontaneous tumor formation

vision/eye
• hypoxia-induced retinal vasculature exhibits a 63% reduction in vascular glomeruli and a 53% reduction in vessel branching compared to in wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory