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Phenotypes Associated with This Genotype
Genotype
MGI:3808612
Allelic
Composition		 Nfasctm1.1Brp/Nfasctm1.1Brp
Tg(Plp1-Nfasc*)1Brp/0
Genetic
Background		 B6.Cg-Nfasctm1.1Brp Tg(Plp1-Nfasc*)1Brp
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfasctm1.1Brp mutation (0 available); any Nfasc mutation (59 available)
Tg(Plp1-Nfasc*)1Brp mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal sciatic nerve morphology ( J:107591 )
• despite the re-establishment of paranodal junctional complexes, the node complex is not rescued

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory