Analysis Tools
mortality/aging
|
• though alive 1 day before birth, fewer than expect mice survive the 2 to 3 hours after birth before nursing
|
endocrine/exocrine glands
|
• at E16, mice have fewer glucagon producing cells than in wild-type mice
• however, the number of glucagon producing cells at E12 is normal
|
|
• mice lack a pancreas
• however, all endocrine islet cell types are detected after birth in the mesentery that normally harbors the pancreas until E16
|
homeostasis/metabolism
hypoglycemia
(
J:51571
)
|
• at birth
|
hematopoietic system
|
• unlike in wild-type mice, glucagon producing cells and pancreatic endocrine cells are located in the spleen at birth
|
growth/size/body
|
• at birth
|
immune system
|
• unlike in wild-type mice, glucagon producing cells and pancreatic endocrine cells are located in the spleen at birth
|
