Phenotypes Associated with This Genotype

Genotype
MGI:3808158

• Allelic Composition: Egflam^tm1Tfir/Egflam^tm1Tfir
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal retina cone cell morphology ( J:138693 )

• absence of the tips of the bipolar cell dendrites in cone ribbon synapses

abnormal retina rod cell morphology ( J:138693 )

• absence of the tips of the bipolar cell dendrites in rod ribbon synapses

vision/eye

abnormal retina cone cell morphology ( J:138693 )

• absence of the tips of the bipolar cell dendrites in cone ribbon synapses

abnormal retina rod cell morphology ( J:138693 )

• absence of the tips of the bipolar cell dendrites in rod ribbon synapses

abnormal eye physiology ( J:138693 )

• sensitivity to small angle stripes was significantly impaired in the optokinetic responses

abnormal cone electrophysiology ( J:138693 )

• the signal transmission from the cone photoreceptor to the cone bipolar cell is impaired

abnormal rod electrophysiology ( J:138693 )

• the signal transmission from the rod photoreceptor to the rod bipolar cell is less sensitive and is delayed