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Phenotypes Associated with This Genotype
Genotype
MGI:3807567
Allelic
Composition		 Runx1tm1Itan/Runx1tm1Itan
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx1tm1Itan mutation (0 available); any Runx1 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:132661 )
N
• early hematopoiesis and myeloid cell differentiation proceed normally in null mutants
• thymocyte differentiation does not show significant differences compared to wild-type

immune system
immune system phenotype ( J:132661 )
N
• thymocyte differentiation does not show significant differences compared to wild-type
• early hematopoiesis and myeloid cell differentiation proceed normally in null mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory