Phenotypes Associated with This Genotype

Genotype
MGI:3807531

• Allelic Composition: Flvcr1^tm1.1Jlab/Flvcr1^tm1.1Jlab
• Genetic Background: B6.129S4-Flvcr1^tm1.1Jlab

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:132057 )

• Background Sensitivity: dead but morphologically identifiable homozygous embryos are found E12.5, while on a mixed background, mutants surviving past E7.5 are alive and indistinguishable from littermates at E12.5

limbs/digits/tail

abnormal limb development ( J:132057 )

• Background Sensitivity: limbs are abnormal but this phenotype is less apparent than on a mixed background and when death occurs prior to E14.5

craniofacial

abnormal craniofacial morphology ( J:132057 )

• Background Sensitivity: defects are observed but are less apparent than on mixed background and when death occurs prior to E14.5