Phenotypes for Nat1 MGI:3807280 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nat1^Rgsc1523/Nat1^Rgsc1523
Genetic Background	involves: C57BL/6 * DBA/2

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Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nat1^Rgsc1523 mutation (0 available); any Nat1 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

abnormal enzyme/coenzyme activity ( J:134504 )

• hepatic N-acteyltransferase 1 activity is reduced by 90% compared to wild-type

reproductive system

reduced fertility ( J:134504 )

• homozygous matings produced only 1 litter each for 2 breeding pairs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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