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Phenotypes Associated with This Genotype
Genotype
MGI:3806705
Allelic
Composition		 Arxtm1Gldn/Y
Tg(Pou3f4-cre)32Cren/0
Genetic
Background		 involves: 129/Sv * C57BL/6 * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arxtm1Gldn mutation (0 available); any Arx mutation (20 available)
Tg(Pou3f4-cre)32Cren mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased brain size ( J:138839 )
• whole brain is smaller than wild-type brain at E18.5
abnormal cerebral cortex morphology ( J:138839 )
• normal distribution of interneurons in cerebral cortex is lost in mutants, with Calb1+ interneurons restricted to subcortical and subventricular regions
abnormal olfactory bulb morphology ( J:138839 )
• olfactory bulbs are nearly absent at E18.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory