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Phenotypes Associated with This Genotype
Genotype
MGI:3806484
Allelic
Composition		 Rgsc545/Rgsc545+
Genetic
Background		 involves: C57BL/6JJcl * DBA/2JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rgsc545 mutation (1 available); any Rgsc545 mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating cholesterol level ( J:133634 )
• 53.9 mg/dL vs. a control range of 68-119 mg/dL
decreased circulating HDL cholesterol level ( J:133634 )
• 27.5 mg/dL vs. a control range of 42-74 mg/dL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory