Mouse Genome Informatics
ht
    Robo1tm1Phr/Robo1+
involves: 129P2/OlaHsd * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
tumorigenesis
• spontaneously develop lung lymphomas and carcinomas during the second year of life with a 3-fold increase in incidence compared with controls
• spontaneously develop lung lymphomas and carcinomas during the second year of life with a 3-fold increase in incidence compared with controls
• 26.5% of tumors that develop in heterozygotes are lung adenocarcinomas

Mouse Models of Human Disease
OMIM IDRef(s)
Lung Cancer 211980 J:93666