Phenotypes for Hc MGI:3806150 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hc⁰/Hc⁰
Genetic Background	B10.D2-Hc⁰ H2^d H2-T18^c/oSnJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hc⁰ mutation (23 available); any Hc mutation (123 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:128218 )

N	• mice exhibit normal ethanol-induced liver steatosis

decreased susceptibility to injury ( J:128218 )

• following exposure to ethanol, mice do not exhibit an increase in alanine aminotransferase, TNF-alpha, IL6 and IFN-gamma as in similarly treated wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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