Analysis Tools
mortality/aging
|
• mice die between E10.5 and E11.5 of abnormality in mesenchymal tissues
|
reproductive system
|
• at somite stage, 2 of 21 mice have a few primordial germ cells whereas the remaining mice have none
|
|
• no primordial germ cells are detected at E7.5 and by early somite stage 19 of 21 mice have no detectable primordial germ cells
|
embryo
|
• despite normal development and differentiation of mesoderm, mice die between E10.5 and E11.5 of abnormality in mesenchymal tissues
|
|
• mice exhibit a delay in allantois development
• Background Sensitivity: mice exhibit a more severe delay in allantois development when further backcrossed onto a C57BL/6 background
|
cellular
|
• at somite stage, 2 of 21 mice have a few primordial germ cells whereas the remaining mice have none
|
|
• no primordial germ cells are detected at E7.5 and by early somite stage 19 of 21 mice have no detectable primordial germ cells
|
