mortality/aging
• 15% of mice die at birth from exencephaly
|
nervous system
• some E10 embryos have neural tubes with openings at the forebrain/midbrain boundary
|
• forebrain overgrowth in the 15% of mice that have exencephaly
|
• disorganization and the absence of parts of the mid-brain are noted in the 15% of mice born with exencephaly
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exencephaly
(
J:134591
)
• 15% of mice are born with exencephaly
• excencephaly results from forebrain overgrowth and ventricular stenosis
|
embryo
• some E10 embryos have neural tubes with openings at the forebrain/midbrain boundary
|