Phenotypes for Del(4Cdkn2a-Cdkn2b)1Brn MGI:3804858 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Del(4Cdkn2a-Cdkn2b)1Brn/+
Genetic Background	involves: 129P2/OlaHsd

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♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased tumor incidence ( J:125189 )

• phenotype is stated to be identical to that of Cdkn2a/Cdkn2b^tm1Brn heterozygotes; however no data is presented in J:125189

increased skin tumor incidence ( J:125189 )

increased leukemia incidence ( J:125189 )

increased lymphoma incidence ( J:125189 )

increased sarcoma incidence ( J:125189 )

integument

increased skin tumor incidence ( J:125189 )

digestive/alimentary system

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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