Analysis Tools
mortality/aging
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• mice die at 2 to 4 months of age
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nervous system
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• at P15, Bergmann glial cell processes are severely disorganized
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• mice exhibit a delay in the migration of cells from the external granule layer to the internal granule layer
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• reduced at P9
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• at P9, the external granule cell layer contains more granule cells than in wild-type mice
• unlike in wild-type mice, granule cells are maintained at P17 but migrate to the internal granule cell layer by P21
• however, cell proliferation within the external granule layer is normal
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• at P9
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growth/size/body
cellular
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• at P15, Bergmann glial cell processes are severely disorganized
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• mice exhibit a delay in the migration of cells from the external granule layer to the internal granule layer
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