About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3804179
Allelic
Composition		 Itgb4tm1Mfel/Itgb4tm1Mfel
Tg(Mpz-cre)26Mes/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgb4tm1Mfel mutation (0 available); any Itgb4 mutation (106 available)
Tg(Mpz-cre)26Mes mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal myelin sheath morphology ( J:137852 )
• progressive increase in the number of myelin infoldings in the sciatic nerve, digital nerve, and anterior roots after 12 months of age

behavior/neurological
behavior/neurological phenotype ( J:137852 )
N
• despite loss of expression in Schwann cells, no tremors, gait abnormalities, or motor skill impairments are detected

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory