About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3803967
Allelic
Composition		 Akt2tm1.1Mbb/Akt2tm1.1Mbb
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akt2tm1.1Mbb mutation (2 available); any Akt2 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:135903 )
N
• no abnormalities in T cell development are observed

homeostasis/metabolism
hyperglycemia ( J:160759 )
• about 25-30% increase in fasting glucose levels at 1 month of age
impaired glucose tolerance ( J:160759 )
• glucose intolerance
decreased liver triglyceride level ( J:160759 )
• 2-fold decrease in liver triglyceride levels

liver/biliary system
decreased liver triglyceride level ( J:160759 )
• 2-fold decrease in liver triglyceride levels

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory