Phenotypes Associated with This Genotype

Genotype
MGI:3803777

• Allelic Composition: Raver1^tm1Hha/Raver1^tm1Hha
• Genetic Background: B6.129S2-Raver1^tm1Hha

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

reduced long-term potentiation ( J:137591 )

• at 2 to 3 weeks and 3 and 8 months of age, mice exhibit decreased early and late long term potentiation (LTP) compared to in wild-type mice and a decline in overall LTP over time

• while mice are able to initiate, maintenance of LTP is defective

reduced long-term depression ( J:137591 )

• at 2-3 weeks of age

cellular

cellular phenotype ( J:137591 )

N • despite interactions with cytoskeletal proteins, mouse embryonic fibroblasts behave normally in culture