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Phenotypes Associated with This Genotype
Genotype
MGI:3803750
Allelic
Composition		 Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm5(HBG1,HBB*)Tow/Hbbtm5(HBG1,HBB*)Tow
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hbatm1(HBA)Tow mutation (3 available); any Hba mutation (10 available)
Hbbtm5(HBG1,HBB*)Tow mutation (0 available); any Hbb mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
anemia ( J:137709 )
• slightly thalassemic
abnormal erythrocyte physiology ( J:137709 )
• modest but significant increase in erythrocyte oxygen affinity

cardiovascular system
cardiovascular system phenotype ( J:137709 )
N
• despite the absence of S-nitrosohemoglobin no signs of pulmonary hypertension or changes in hypoxic vasodilation response are seen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory