Analysis Tools
growth/size/body
weight loss
(
J:135154
)
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• weight loss is noted in mice starting at 6 weeks of age
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immune system
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• mice 10 weeks of age have severe lymphocytic infiltration of the salivary glands
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• occurs in mice by 10 weeks of age
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• severe thyroiditis is observed in mice 15 to 25 weeks in age
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• mice 10 weeks of age have severe lymphocytic infiltration of the lacrimal glands
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• mice 10 weeks have age have severe lymphocytic infiltration of the pancreas
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• there is increased percentage of CD4 T cells in the spleen that are activated based on surface marker expression (CD62Llo CD44hi)
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• lymphocyte infiltrates are found in mice by 10 weeks of age
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endocrine/exocrine glands
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• mice 10 weeks of age have severe lymphocytic infiltration of the salivary glands
|
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• severe thyroiditis is observed in mice 15 to 25 weeks in age
|
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• mice 10 weeks of age have severe lymphocytic infiltration of the lacrimal glands
|
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• mice 10 weeks have age have severe lymphocytic infiltration of the pancreas
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respiratory system
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• lymphocyte infiltrates are found in mice by 10 weeks of age
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digestive/alimentary system
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• mice 10 weeks of age have severe lymphocytic infiltration of the salivary glands
|
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• occurs in mice by 10 weeks of age
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vision/eye
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• mice 10 weeks of age have severe lymphocytic infiltration of the lacrimal glands
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hematopoietic system
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• there is increased percentage of CD4 T cells in the spleen that are activated based on surface marker expression (CD62Llo CD44hi)
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