Phenotypes for Fgf8 Gli3 MGI:3803097 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fgf8^tm1.4Mrt/Fgf8⁺ Gli3^tm1.1Alj/Gli3^tm1.1Alj
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf8^tm1.4Mrt mutation (0 available); any Fgf8 mutation (18 available)
Gli3^tm1.1Alj mutation (0 available); any Gli3 mutation (80 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:137136 )

N	• cerebellum has begun to foliate at birth • granule layer extends along the anterior posterior length of the cerebellum • isthmus is formed • Purkinje cells are normal

absent inferior colliculus ( J:137136 )

• not clearly distinguishable

enlarged tectum ( J:137136 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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