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Phenotypes Associated with This Genotype
Genotype
MGI:3803017
Allelic
Composition		 Ptdss1tm1Jev/Ptdss1tm1Jev
Ptdss2Gt(KST314)Byg/Ptdss2+
Genetic
Background		 involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptdss1tm1Jev mutation (0 available); any Ptdss1 mutation (36 available)
Ptdss2Gt(KST314)Byg mutation (0 available); any Ptdss2 mutation (72 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:137106 )
N
• despite reduction in phosphatidylserine levels, mice exhibit a normal lifespan

homeostasis/metabolism
abnormal phospholipid level ( J:137106 )
• phospatidylserine levels are reduced by 40% in brain, by 29% in liver, and by 33% in heart compared to in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory