Analysis Tools
immune system
| N |
• despite the reduction in CD3+ T cells, total leukocyte and lymphocyte counts are normal and mice do not exhibit hypogammaglobulinemia
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• mice exhibit an almost complete block in thymocyte development at the transition from CD4+CD8+ double positive to CD4+ or CD8+ single-positive T cells
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• peripheral CD3+ T cells are almost completely absent
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• in the thymus
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• in the thymus
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• mice fail to mount a humoral immune response when stimulated
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• up to 100-fold
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hematopoietic system
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• mice exhibit an almost complete block in thymocyte development at the transition from CD4+CD8+ double positive to CD4+ or CD8+ single-positive T cells
|
|
• peripheral CD3+ T cells are almost completely absent
|
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• in the thymus
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• in the thymus
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• up to 100-fold
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