Analysis Tools
hematopoietic system
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• 2.5% of splenic B cells express human mu heavy chain
• half of the B cells that express human mu heavy chain do not express the endogenous murine mu chain
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• the VDJ segments of the human transgene undergo recombination within B cells
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• antibodies containing the human mu heavy chain is found in the sera at 0.7 micrograms per ml
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immune system
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• 2.5% of splenic B cells express human mu heavy chain
• half of the B cells that express human mu heavy chain do not express the endogenous murine mu chain
|
|
• the VDJ segments of the human transgene undergo recombination within B cells
|
|
• antibodies containing the human mu heavy chain is found in the sera at 0.7 micrograms per ml
|
