Phenotypes Associated with This Genotype

Genotype
MGI:3802636

• Allelic Composition: Rptor^tm1Lex/Rptor^tm1Lex
• Genetic Background: involves: 129S/SvEvBrd

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:137592 )

• mice implant but fail to expand thereafter and die

embryo

decreased inner cell mass proliferation ( J:137592 )

• inner cell mass explants exhibit reduced expansion in culture unlike wild-type explants

abnormal trophoblast giant cell morphology ( J:137592 )

• explants exhibit reduced expansion in culture unlike wild-type explants

cellular

decreased inner cell mass proliferation ( J:137592 )

• inner cell mass explants exhibit reduced expansion in culture unlike wild-type explants