immune system
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• the number of mature T cells in the spleen is less than 10% of wild-type
|
|
• slight increase in the frequency
|
|
• the number of mature T cells in the spleen is less than 10% of wild-type
|
|
• the frequency of total CD4+ thymocytes and mature CD4+ thymocytes is decreased compared to in wild-type mice
• few CD4+ T cells are detected
|
|
• the frequency of CD8+ T cells is reduced by greater than 80% compared to in wild-type mice
• the frequency of mature CD8+ thymocytes is reduced over 10-fold compared to in wild-type mice
• few CD8+ T cells are detected
|
hematopoietic system
|
• the number of mature T cells in the spleen is less than 10% of wild-type
|
|
• slight increase in the frequency
|
|
• the number of mature T cells in the spleen is less than 10% of wild-type
|
|
• the frequency of total CD4+ thymocytes and mature CD4+ thymocytes is decreased compared to in wild-type mice
• few CD4+ T cells are detected
|
|
• the frequency of CD8+ T cells is reduced by greater than 80% compared to in wild-type mice
• the frequency of mature CD8+ thymocytes is reduced over 10-fold compared to in wild-type mice
• few CD8+ T cells are detected
|
cellular
|
• the number of mature T cells in the spleen is less than 10% of wild-type
|


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