immune system
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• apoptosis of DN thymocytes is increased 2-fold compared to in wild-type mice
|
|
• thymus contain 5% of the cells found in wild-type mice
|
|
• T cell development is blocked between DN2/3 and DN4 stages
• apoptosis of DN thymocytes is increased 2-fold compared to in wild-type mice
|
|
• 5% to 10% of wild-type
|
|
• 40% of wild-type
|
|
• T cell numbers in the spleen are 40% to 50% of wild-type
|
|
• 5% to 10% of wild-type
|
|
• 5% to 10% of wild-type
|
hematopoietic system
|
• apoptosis of DN thymocytes is increased 2-fold compared to in wild-type mice
|
|
• thymus contain 5% of the cells found in wild-type mice
|
|
• T cell development is blocked between DN2/3 and DN4 stages
• apoptosis of DN thymocytes is increased 2-fold compared to in wild-type mice
|
|
• T cell numbers in the spleen are 40% to 50% of wild-type
|
|
• 5% to 10% of wild-type
|
|
• 40% of wild-type
|
|
• 5% to 10% of wild-type
|
|
• 5% to 10% of wild-type
|
cellular
|
• apoptosis of DN thymocytes is increased 2-fold compared to in wild-type mice
|
endocrine/exocrine glands
|
• thymus contain 5% of the cells found in wild-type mice
|


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