Mouse Genome Informatics
hm
    Efemp1tm1Eap/Efemp1tm1Eap
involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
vision/eye
• homozygotes develop deposits of material between Bruch's membrane and the retinal pigment epithelium by 12 months of age, which resemble basal deposits in individuals with age-related macular degeneration
• extensive vacuolization and loss of basolateral infoldings

pigmentation
• extensive vacuolization and loss of basolateral infoldings

Mouse Models of Human Disease
OMIM IDRef(s)
Doyne Honeycomb Retinal Dystrophy; DHRD 126600 J:129901