Analysis Tools
endocrine/exocrine glands
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• female mice exhibit abnormal ductal trees
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• alveoli exhibit denser cell lining in the walls compared to Tg(MMTVTGFA)29Rjc expressing mice that exhibit cystically dilated alveoli
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• 50% of mice exhibit mammary gland tumors at day 175 and 95% at day 250 compared to 6% of Tg(MMTVTGFA)29Rjc expressing mice and 35% of Tg(MMTVneu)202Mul expressing mice at day 250
• mice exhibit tumors that are nodular or tubular but not mixed
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• nulliparous female mice exhibit epithelial hyperplasia and dysplasia along with stromal inflammation
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neoplasm
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• 50% of mice exhibit mammary gland tumors at day 175 and 95% at day 250 compared to 6% of Tg(MMTVTGFA)29Rjc expressing mice and 35% of Tg(MMTVneu)202Mul expressing mice at day 250
• mice exhibit tumors that are nodular or tubular but not mixed
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behavior/neurological
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• females cannot nurse her young
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integument
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• female mice exhibit abnormal ductal trees
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• alveoli exhibit denser cell lining in the walls compared to Tg(MMTVTGFA)29Rjc expressing mice that exhibit cystically dilated alveoli
|
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• 50% of mice exhibit mammary gland tumors at day 175 and 95% at day 250 compared to 6% of Tg(MMTVTGFA)29Rjc expressing mice and 35% of Tg(MMTVneu)202Mul expressing mice at day 250
• mice exhibit tumors that are nodular or tubular but not mixed
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• nulliparous female mice exhibit epithelial hyperplasia and dysplasia along with stromal inflammation
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