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Phenotypes Associated with This Genotype
Genotype
MGI:3798423
Allelic
Composition
Rgsc396/Rgsc396+
Genetic
Background
involves: C57BL/6JJcl * DBA/2JJcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rgsc396 mutation (1 available); any Rgsc396 mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• mice heterozygous for this mutation exhibit a small extra toe on the preaxial margin of the hindfoot
• heterozygous mutant mice display thickening of the second digit of the forefoot, which may be an elongated first digit fused with the second digit

nervous system
• rarely, hydrocephaly with a white spot is observed

pigmentation
• rarely, hydrocephaly with a white spot is observed

integument
• rarely, hydrocephaly with a white spot is observed


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory