Mouse Genome Informatics
cn
    Myocdtm1Msp/Myocdtm1Msp
Tg(Pax3-cre)1Joe/0

involves: 129/Sv * C57BL/6 * SJL
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• all mutants at P2 exhibit patent ductus arteriosus
• E16.5 mutants exhibit diminished expression of smooth muscle cell contractile proteins in the ductus arteriosus
• however, patterning of the cardiac outflow tract and great arteries is normal

cellular
• all mutants at P2 exhibit patent ductus arteriosus
• E16.5 mutants exhibit diminished expression of smooth muscle cell contractile proteins in the ductus arteriosus
• however, patterning of the cardiac outflow tract and great arteries is normal

Mouse Models of Human Disease
OMIM IDRef(s)
Patent Ductus Arteriosus 607411 J:131288