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Phenotypes Associated with This Genotype
Genotype
MGI:3797085
Allelic
Composition
Gt(ROSA)26Sortm1(Trpv1,ECFP)Mde/Gt(ROSA)26Sor+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Trpv1,ECFP)Mde mutation (1 available); any Gt(ROSA)26Sor mutation (942 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• capsaicin infusion after focal induction of Trpv1 expression in subsets of striatal neurons by injection of a lentiviral-cre vector recapitulates contralateral circling behavior at one week post-injection; circling subsides within 15 minutes of capsaicin application
• ipsilateral circling is not observed after capsaicin infusion


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory