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Phenotypes Associated with This Genotype
Genotype
MGI:3796623
Allelic
Composition		 Mpltm1Wsa/Mpltm1Wsa
Suz12Plt8/Suz12Plt8
Genetic
Background		 B6.Cg-Mpltm1Wsa Suz12Plt8
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mpltm1Wsa mutation (1 available); any Mpl mutation (48 available)
Suz12Plt8 mutation (0 available); any Suz12 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:136262 )
• no homozygous Suz12Plt8Hiltanimals were found, indicating prenatal lethality
• embryos homozygous for Suz12Plt8Hilt were reduced in number at embryonic day 8.5

embryo
decreased embryo size ( J:136262 )
• embryos homozygous for Suz12Plt8Hilt were smaller than wild-type

growth/size/body
decreased embryo size ( J:136262 )
• embryos homozygous for Suz12Plt8Hilt were smaller than wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory