Phenotypes Associated with This Genotype

Genotype
MGI:3795754

• Allelic Composition: Plxna2^nmf454/Plxna2^nmf454
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

decreased neuronal migration ( J:135408 )

• in migrating granule cells the average distance between the centrosome and nucleus is decreased

ectopic cerebellar granule cells ( J:135408 )

• many granule cells are present in the molecular layer

abnormal cerebellar molecular layer ( J:135408 )

• hypercellular

behavior/neurological

ataxia ( J:135408 )

• subtle ataxic gait, not seen in all homozygotes

growth/size/body

decreased body size ( J:135408 )

cellular

decreased neuronal migration ( J:135408 )

• in migrating granule cells the average distance between the centrosome and nucleus is decreased