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Phenotypes Associated with This Genotype
Genotype
MGI:3795671
Allelic
Composition		 Pkd1tm2Som/Pkd1tm2Som
Tg(Pkhd1-cre)1Igr/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pkd1tm2Som mutation (0 available); any Pkd1 mutation (151 available)
Tg(Pkhd1-cre)1Igr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
abnormal kidney morphology ( J:135301 )
• at P24, proliferation of the cyst lining cells in the kidney is increased compared to in wild-type mice

growth/size/body
kidney cyst ( J:135301 )

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory