Phenotypes Associated with This Genotype

Genotype
MGI:3795605

• Allelic Composition: Pkd1^tm1Som/Pkd1⁺; Pkd2^tm2Som/Pkd2⁺
• Genetic Background: involves: 129/Sv * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

liver/biliary system

liver cyst ( J:78422 )

• at 12 months of age, 43% of livers exhibit cysts

• mice exhibit more cysts than in wild-type mice or either heterozygote alone

renal/urinary system

kidney cyst ( J:78422 )

• at 12 months of age, 29% of kidneys exhibit gross kidney surface cysts with only 1 observed at 9 months of age

• mice exhibit more cysts than in wild-type mice or either heterozygote alone

growth/size/body

kidney cyst ( J:78422 )

• at 12 months of age, 29% of kidneys exhibit gross kidney surface cysts with only 1 observed at 9 months of age

• mice exhibit more cysts than in wild-type mice or either heterozygote alone

liver cyst ( J:78422 )

• at 12 months of age, 43% of livers exhibit cysts

• mice exhibit more cysts than in wild-type mice or either heterozygote alone