About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3794755
Allelic
Composition		 Ppp4ctm1.2Htn/Ppp4ctm1.2Htn
Genetic
Background		 involves: 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp4ctm1.2Htn mutation (0 available); any Ppp4c mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality between implantation and somite formation, complete penetrance ( J:134682 )
• homozygous mice died between E4.5 and E7.5, soon after implantation

embryo
inner cell mass degeneration ( J:134682 )
• inner cell mass cells of homozygous null blastocyst explants in culture grew poorly after 3 days and degenerated soon thereafter

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory