Phenotypes Associated with This Genotype

Genotype
MGI:3794451

• Allelic Composition: Pmp22^Tr/?
• Genetic Background: involves: CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal Schwann cell morphology ( J:98118 )

• Schwann cell density is increased from P4 onwards compared to in wild-type mice

• at P10 and 10 weeks of age, Schwann cell proliferation is increased compared to in wild-type mice

• at P21 and 10 weeks of age, mice exhibit increased Schwann cell apoptosis compared to in wild-type mice

cellular

abnormal Schwann cell morphology ( J:98118 )

• Schwann cell density is increased from P4 onwards compared to in wild-type mice

• at P10 and 10 weeks of age, Schwann cell proliferation is increased compared to in wild-type mice

• at P21 and 10 weeks of age, mice exhibit increased Schwann cell apoptosis compared to in wild-type mice