Phenotypes Associated with This Genotype

Genotype
MGI:3794284

• Allelic Composition: Pmp22^Tr/Pmp22^Tr
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:27475 )

N • mice have normal a lifespan

nervous system

abnormal Schwann cell morphology ( J:27475 )

• Shwann cells attach to axons but fail to form myelin

demyelination ( J:27475 )

• axons are virtually devoid of myelin

behavior/neurological

tremors ( J:27475 )

abnormal gait ( J:27475 )

cellular

abnormal Schwann cell morphology ( J:27475 )

• Shwann cells attach to axons but fail to form myelin